Posts Tagged ‘Preclinical Research’
How to Improve Humanized Mouse Engraftment: CD34+ Cell Sourcing & Viability Tips
By: Joanna Wirkus Simple Steps to Significantly Improve Humanized Mice Engraftment Success Previously in “Overcoming Challenges with Animal Models in Research”, we covered why animal models with human immune systems have significantly improved the translation of preclinical findings into life-saving treatments. Successfully creating these advanced models for testing new therapies relies on high hematopoietic stem…
For More InformationCryopreservation in Cell and Gene Therapy: Ensuring High-Viability Cells for Research & Manufacturing
By Joanna Wirkus The Role of Cryopreservation in Cell and Gene Therapy Cryopreservation is a cornerstone of cell and gene therapy, enabling the long-term storage and viability of vital cell types such as CD34+ hematopoietic stem cells, mesenchymal stem cells (MSCs), natural killer (NK) cells, and T cells used in CAR-T therapies. Interestingly, nature has…
For More InformationOptimizing Gene and Cell Therapy Research by Starting with Properly Sourced Human Bone Marrow Cells
By: Joanna Wirkus Bone Marrow Cells: Critical Tools Driving Stem Cell and Gene Therapy Innovation Surprisingly safe and well tolerated, the first bone marrow biopsy was performed on the shinbone in 1908 by Italian physician Giovanni Ghedini. Today, bone marrow continues to be an important source of information about the health status of individuals with…
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