Mobilized Peripheral Blood Leukopaks

Your source for quality fresh and cryopreserved human cells

Human Mobilized Peripheral Blood Leukopaks are collected from healthy IRB consented donors that are injected with Granulocyte-Colony Stimulating Factor (G-CSF aka Neupogen^®), Plerixafor (aka Mozobil^®), or a combination of Plerixafor and G-CSF, which increases circulating leukocytes and stimulates the bone marrow to produce a large number of hematopoietic and progenitor stem cells and mobilizes these cells into the bloodstream, allowing for enriched CD34+ hematopoietic stem cells from a single donor as compared to traditional Leukopaks. Collecting CD34+ stem cells from a single donor eliminates donor-to-donor variation, allows scalability of stem cell studies, and decreases same cell variability. Mobilized Leukopaks are ideal for stem cell studies relating to regenerative medicine, immunotherapy, and transplant therapy.

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Popular Mobilized Peripheral Blood Leukopaks

Fresh Mobilized Leukopaks | G-CSF + Plerixafor

Fresh Mobilized Leukopaks | G-CSF

Fresh Mobilized Leukopaks | G-CSF+ Plerixafor

Your Cells, Your Way!

HIGH-QUALITY MOBILIZED LEUKOPAKS

Cell-rich Mobilized Leukopaks are extracted using an FDA-approved apheresis machine. Once collected, Mobilized Leukopaks are sent out on the day of collection to ensure you receive a fresh product.

2x10¹⁰ TNCs/full bag
Enriched CD34+ cells
Highly-enriched PBMCs
≥90% viability
HBV, HCV, HIV negative
IRB approved

Figure 1. Representative flow data of the viability and purity of peripheral blood mononuclear cells from a Leukopak prior to cryopreservation.

DONOR SELECTION

Extensive donor pool
Specific donor demographics (age, weight, ethnicity, etc.)
Donor lifestyle characteristics (BMI, smoker/non-smoker, etc.)
Medical history (allergies, medications, etc.)
HLA, RhD, and ABO typing available
Additional infectious disease screening (CMV, etc.)
Much more....

CELL COLLECTION/PROCESSING

Special processing procedures available
Different mobilization agents available

EXPEDIENCY FROM ORDER TO DELIVERY

Custom media and buﬀer
Customizable packaging options
Cryo shipping available
FedEx^®, World Courier^®, UPS^®
Same day delivery in select cities

Frequently Asked Questions

What mobilization agents do you use?

Can I get LCMV testing done on a mobilized Leukopak?

Where can CGT Global ship products?

Why does CGT Global offer different mobilization agents?

CGT Global offers PBMCs and CD34+ stem cells mobilized with G-CSF, Plerixafor, and G-CSF plus plerixafor. The mechanism of action of these mobilization agents, and the combination of them, have been shown to change the expression profile, cell composition, and engraftment potential of the mobilized cells.^1,2,3 Therefore, it is important to understand that switching mobilization reagents during a study may also change the mobilized cell type and their effect on studies relating to transplantation and stem cell research.

1. Broxmeyer, et al. (2005) Rapid mobilization of murine and human hematopoietic stem and progenitor cells with AMD3100, a CXCR4 antagonist. J Exp Med. 201(8):1307–1318.
2. Larochelle, et al. (2006) AMD3100 mobilizes hematopoietic stem cells with long-term repopulating capacity in nonhuman primates. Blood. 107(9):3772–3778.
3. Lidonnici, et al. (2017) Plerixafor and G-CSF combination mobilizes hematopoietic stem and progenitors cells with a distinct transcriptional profile and a reduced in vivo homing capacity compared to plerixafor alone. Haematol. 102(4):120-124.