HUMAN PRIMARY CELLS FOR RESEARCH

Human PBMCs for Research

CGT Global supplies human peripheral blood mononuclear cells, PBMCs, for immunology, cell therapy research, drug discovery, assay development, immune monitoring, biomarker research, and translational studies.

Researchers can access cryopreserved PBMCs, mobilized PBMCs, disease state donor material, isolated immune cell populations, and custom cell isolation support based on project requirements.

Need a specific disease state, donor profile, cell quantity, or research application? Our team can review current inventory and help identify the most appropriate material for your study.

Request PBMC Availability and Pricing Explore PBMC Options

PBMC SOURCING OPTIONS

Human PBMC Products and Sourcing Options

Different research programs require different PBMC formats, donor profiles, and cell quantities. CGT Global supports standard PBMC sourcing as well as specialized projects involving disease state donors, mobilized material, isolated immune cells, and custom processing.

PBMC Option Material Type Typical Format Common Research Uses
Human PBMCs Peripheral blood donor material Cryopreserved Immune profiling, flow cytometry, ELISpot, cytokine assays, assay development, and drug discovery
Disease State PBMCs Disease state donor material Cryopreserved Biomarker research, disease modeling, immune profiling, and therapeutic development
Mobilized PBMCs Mobilized donor material Cryopreserved Cell therapy research, progenitor focused workflows, and immune cell research
Isolated Immune Cells Selected immune cell populations Cryopreserved Cell specific assays, functional studies, immunology, and drug development
Custom PBMC Isolation Project specific starting material Custom Bulk isolation, donor specific research, and specialized workflows

AVAILABLE PRODUCTS

Browse Human PBMC Products

Explore available human PBMC products and sourcing options. Select a product below to review specifications, available formats, and additional research information.

Browse Products

DISEASE STATE DONOR MATERIAL

Disease State PBMCs for Research

Disease state PBMCs can help researchers evaluate immune function, cellular phenotypes, biomarkers, therapeutic response, and disease associated biological differences using donor material relevant to the population being studied.

CGT Global maintains disease state PBMC and mononuclear cell inventory across select autoimmune, oncology, infectious disease, and specialty donor populations.

Autoimmune and Inflammatory

Autoimmune Disease PBMCs

  • Systemic Lupus Erythematosus, SLE
  • Rheumatoid Arthritis, RA
  • Combined SLE and Rheumatoid Arthritis
  • Sjögren's Syndrome
  • Hashimoto's Disease
Oncology

Oncology PBMCs

  • Acute Myeloid Leukemia, AML
  • Chronic Lymphocytic Leukemia, CLL
  • Breast Cancer
  • Multiple Myeloma
Infectious Disease

Infectious Disease PBMCs

  • HIV
  • Hepatitis C Virus, HCV
  • Lyme Disease
Specialty Donors

Additional Disease State Material

  • Thoracic Endometriosis
  • Additional specialty donor profiles
  • Project specific sourcing opportunities
Looking for a specific disease state?

Disease state inventory changes as material is allocated and new donor material becomes available. Contact CGT Global to confirm current donor availability, cell quantities, documentation, and study fit.

Request Current Disease State Inventory Explore Disease State Products

CUSTOM SOURCING

Looking for a Specific Disease State or Donor Profile?

Finding the right PBMC donor can be as important as selecting the right cell type.

If existing inventory does not meet your study requirements, CGT Global can evaluate projects involving specific donor characteristics, disease states, inclusion criteria, exclusion criteria, sample requirements, and downstream processing needs.

Our team can help determine whether your project can be supported through existing cryopreserved inventory or requires a more customized sourcing approach.

Tell us what your study requires

  • Disease state
  • Donor demographics
  • Collection criteria
  • Required cell quantity
  • Research application
  • Processing requirements
  • Documentation needs
  • Additional donor characteristics
Discuss a Custom PBMC Project

HEALTHY DONOR MATERIAL

Healthy Donor PBMCs for Research

Healthy donor PBMCs are commonly used as controls, reference samples, and primary research material across immunology, drug discovery, assay development, and cell based research.

PBMCs provide access to multiple immune cell populations within the same sample and can support the evaluation of immune response, donor variability, cellular function, activation, and therapeutic activity.

CGT Global can help researchers evaluate current healthy donor PBMC availability based on cell quantity, donor criteria, project requirements, and available documentation.

Check Healthy Donor PBMC Availability

PBMC BASICS

What Are PBMCs?

Peripheral blood mononuclear cells, commonly referred to as PBMCs, are blood cells characterized by a single round nucleus.

Human PBMC populations primarily contain lymphocytes and monocytes, along with smaller populations of other mononuclear immune cells. Because PBMCs contain several important immune cell types in one sample, they are widely used in immunology, drug development, cell therapy research, and translational studies.

For a deeper overview of PBMC biology, cell populations, isolation, and research applications, read our detailed PBMC review.

Read Our PBMC Research Review

T Cells

T cells play central roles in adaptive immunity and include populations such as CD4 positive helper T cells, CD8 positive cytotoxic T cells, memory T cells, and regulatory T cells.

B Cells

B cells support humoral immune responses through antibody production, antigen presentation, and the development of immune memory.

Natural Killer Cells

Natural killer cells contribute to innate immune defense and are commonly studied in oncology, immunotherapy, cytotoxicity, and cell therapy research.

Monocytes

Monocytes are involved in phagocytosis, inflammatory signaling, antigen presentation, immune regulation, and differentiation into other myeloid cell populations.

Dendritic Cell Populations

Dendritic cells are antigen presenting cells involved in immune activation and the regulation of adaptive immune responses.

Need a Specific Cell Population?

Researchers who do not require the full PBMC population can explore isolated immune cells from CGT Global.

Explore Human Isolated Cells

RESEARCH APPLICATIONS

PBMC Research Applications

Human PBMCs are used throughout immunology, pharmaceutical development, biotechnology, and translational research because they provide access to multiple primary human immune cell populations from individual donors.

Flow Cytometry

PBMCs can be used to identify, quantify, and characterize immune cell populations and evaluate surface or intracellular markers.

Immune Profiling

Researchers can use PBMCs to compare immune populations, activation states, cellular phenotypes, and donor specific immune characteristics.

ELISpot and Cytokine Assays

PBMCs support functional immune assays measuring cytokine secretion and antigen specific cellular responses.

Biomarker Research

Healthy and disease state PBMCs can support biomarker discovery and validation programs investigating immune pathways associated with disease or therapeutic response.

Drug Discovery and Therapeutic Development

Primary human PBMCs provide a biologically relevant system for studying drug response, immune modulation, toxicity, and potential therapeutic mechanisms.

Cell Therapy Research

PBMCs and PBMC derived immune populations can support early cell therapy research, process development, functional characterization, and immune cell studies.

Translational Research

PBMCs help connect laboratory findings with human biology by providing primary immune cells from donors with relevant biological and clinical characteristics.

Assay Development

Human PBMCs can support the development and optimization of cell based assays, functional immune assays, and screening workflows.

CHOOSING A DONOR POPULATION

Disease State PBMCs vs Healthy Donor PBMCs

The appropriate PBMC donor population depends on the biological question your study is designed to answer.

Healthy Donor PBMCs

Healthy donor PBMCs are commonly used for baseline studies, assay development, reference populations, and healthy control groups.

Disease State PBMCs

Disease state PBMCs may be preferred when researchers need to study disease associated immune phenotypes, biomarkers, cellular responses, therapeutic targets, or differences between affected and healthy populations.

Some research programs require both populations to establish appropriate comparison groups. If your study requires specific healthy and disease state cohorts, CGT Global can help review current donor availability and project requirements.

Request PBMC Availability View Disease State PBMCs

FLEXIBLE STUDY DESIGN

Cryopreserved PBMCs for Flexible Research Workflows

Cryopreserved PBMCs give researchers access to primary human immune cells without coordinating each experiment around a donor collection schedule.

They can support studies requiring repeated assays, multiple experimental time points, defined donor profiles, healthy and disease state comparisons, or downstream immune cell isolation.

Read the PBMC Viability and Recovery Guide

Common Cryopreserved PBMC Workflows

  • Flow cytometry
  • Immune profiling
  • Repeated functional assays
  • Multi donor studies
  • Healthy and disease state comparisons
  • Multiple experimental time points
  • Downstream cell isolation

CHOOSING STARTING MATERIAL

PBMCs vs Leukopaks

PBMCs and leukopaks are related products, but they serve different research needs.

PBMCs are isolated mononuclear immune cells. Leukopaks are leukapheresis starting material containing a broader population of white blood cells that can be processed into PBMCs or specific isolated cell populations.

Consideration PBMCs Leukopaks
Material Isolated mononuclear cells Leukapheresis starting material
Processing PBMC isolation already completed Additional processing may be required
Typical Scale PBMC assays and cell based research Larger starting material requirements
Immune Cell Access Mixed PBMC populations Broad starting material for downstream isolation
Best Fit Ready to use PBMC workflows Bulk cell requirements and custom isolation

PBMCs may be the better choice when your study requires isolated mononuclear cells ready for downstream assays. Leukopaks may be preferred when your program requires larger quantities of starting material or additional processing flexibility.

Explore Research Leukopaks Explore Mobilized Leukopaks

DOWNSTREAM CELL ISOLATION

Need More Than PBMCs?

Researchers do not always need the full PBMC population. CGT Global also supports access to isolated immune cell populations for more targeted cellular research.

For larger cell requirements or specialized processing, CellsExpress can support bulk cell isolation from relevant starting material.

Explore Isolated Cells Explore CellsExpress

Immune Cell Populations May Include

  • T cells
  • B cells
  • Natural killer cells
  • Monocytes
  • Dendritic cells
  • Additional immune cell populations

MULTI ANALYTE RESEARCH

PBMCs and Complementary Biospecimens

Some research programs require more than one biospecimen type. Depending on donor and inventory availability, CGT Global may be able to support disease state research with additional biospecimens such as plasma or serum.

This can support programs evaluating both cellular and circulating biological signals, including immune profiling, cytokines, biomarkers, antibodies, and other analytes.

Matched sample availability depends on the individual donor and current inventory.

Ask About Complementary Biospecimens

DONOR SELECTION

Donor Criteria and PBMC Documentation

Donor selection can have a significant impact on PBMC research. CGT Global can help researchers evaluate material based on study requirements such as donor characteristics, collection information, product format, cell quantity, documentation, and shipping needs.

For studies requiring specific donor characteristics or testing criteria, contact our team so availability and study fit can be reviewed.

THE CGT GLOBAL DIFFERENCE

Why Researchers Source PBMCs From CGT Global

PBMC sourcing is about more than finding available cells. Research programs also depend on responsive communication, appropriate donor selection, accurate expectations, and practical support when requirements change.

Responsive Scientific Support

Our team works with researchers to understand the material, donor, quantity, and study requirements behind each request.

Transparent Communication

If a requested donor profile, quantity, product, or timeline cannot be supported as requested, we communicate those limitations rather than overpromising.

Project Specific Problem Solving

When a standard product does not fit the study, we evaluate inventory, alternative starting material, isolated cell options, and custom sourcing approaches.

Connected Collection and Processing

Communication across collection, laboratory, scientific, and client facing teams helps researchers evaluate PBMCs, leukopaks, and isolated cell options.

Accountability Throughout the Project

Our goal is to identify issues quickly, communicate clearly, and work toward practical solutions when research requirements change.

PBMC SOURCING

Buy Human PBMCs for Research

CGT Global supplies cryopreserved human PBMCs for research programs requiring primary immune cells from healthy and disease state donors.

PBMCs can support immune profiling, flow cytometry, ELISpot, cytokine assays, biomarker discovery, drug development, cell therapy research, and translational studies.

If you already know your study specifications, include them with your quote request so our team can identify the most relevant available material.

Ask Us About

  • Current PBMC inventory
  • Disease state availability
  • Healthy donor material
  • Cell quantities
  • Donor criteria
  • Mobilized PBMCs
  • Isolated immune cells
  • Custom isolation
  • Documentation
  • Shipping
  • Pricing
Request PBMC Availability and Pricing

PBMC RESEARCH RESOURCES

Learn More About Human PBMCs

Explore additional CGT Global resources related to PBMC biology, viability, starting material, and downstream cell isolation.

PBMC Basics

Peripheral Blood Mononuclear Cells: A Brief Review

Learn more about PBMC biology, immune cell populations, and research applications.

PBMC Quality

Optimizing PBMC Viability and Recovery

Review factors affecting collection, cryopreservation, thawing, and recovery.

Starting Material

Human Leukopaks for Research

Compare PBMCs with larger leukapheresis starting material for downstream cell isolation workflows.

Bulk Isolation

CellsExpress Bulk Cell Isolation

Explore custom isolated immune and stem cell options for larger research programs.

FREQUENTLY ASKED QUESTIONS

Frequently Asked Questions About Human PBMCs

What are PBMCs?

PBMC stands for peripheral blood mononuclear cells. PBMCs include immune cell populations such as T cells, B cells, natural killer cells, and monocytes.

What are PBMCs used for in research?

PBMCs are commonly used in immune profiling, flow cytometry, ELISpot, cytokine assays, biomarker research, drug development, cell therapy research, and translational studies.

Does CGT Global offer disease state PBMCs?

Yes. CGT Global maintains cryopreserved disease state PBMC and mononuclear cell inventory across select autoimmune, oncology, infectious disease, and specialty donor populations. Availability changes as material is allocated and new inventory becomes available.

Can I request PBMCs from a specific donor population?

CGT Global can evaluate requests involving specific donor characteristics, disease states, cell quantities, and study requirements. Availability depends on current inventory and sourcing feasibility.

Are CGT Global PBMCs cryopreserved?

CGT Global supplies cryopreserved PBMC products for research applications. Contact our team for current specifications and availability.

Does CGT Global offer mobilized PBMCs?

Yes. Mobilized PBMC products are available for research workflows requiring material collected following donor mobilization.

What is the difference between PBMCs and leukopaks?

PBMCs are isolated peripheral blood mononuclear cells. Leukopaks are leukapheresis starting material containing a broader mixture of white blood cells that can be further processed into PBMCs or specific immune cell populations.

Can I source plasma or serum for the same disease state?

CGT Global maintains multiple biospecimen types across a range of disease states. Availability of matched or complementary material depends on the individual donor and current inventory.

Does CGT Global offer GMP PBMCs?

CGT Global does not currently offer GMP PBMCs. Researchers requiring GMP starting material should explore CGT Global GMP leukopak options or contact our team to discuss clinical project requirements.

FIND THE RIGHT MATERIAL

Find the Right PBMCs for Your Research

Whether you need standard cryopreserved PBMCs, disease state PBMCs, mobilized PBMCs, isolated immune cells, or support for specialized donor criteria, CGT Global can help evaluate the right sourcing approach.

Tell us the disease state, donor requirements, cell quantity, application, and timeline you are working with.

Request a PBMC Quote