Publications Library
Selected publications, protocols, and supporting studies demonstrating how CGT Global and StemExpress sourced materials are used across immunology, cell therapy, stem cell, and regenerative medicine research.
PBMC
Publications and protocols showing PBMC use in immunology and cell therapy workflows, including examples where PBMCs were purchased directly from StemExpress or isolated from StemExpress sourced starting material.
IVS of healthy donor PBMCs
Bio-protocol · 2025
Protocol describing in vitro stimulation workflows using healthy donor PBMCs in either fresh or cryopreserved format.
“HLA-A*02:01:01+ PBMCs were purchased from StemExpress in either fresh or cryopreserved format.”
Direct StemExpress PBMC citation
CD47 and PD-L1 overexpression in proliferating human hepatocytes promotes immune tolerance
American Journal of Transplantation · 2022
Study using human PBMCs in a T cell assay to evaluate immune tolerance related responses.
“Human peripheral blood mononuclear cells (PBMCs) were purchased from StemExpress...”
Direct StemExpress PBMC citation
Technical considerations and strategies for generating and optimizing humanized immune system models
Computational and Structural Biotechnology Journal · 2024
Review and methods focused article discussing PBMC humanized immune system models and experimental setup.
“Cryopreserved human peripheral blood mononuclear cells (PBMCs) were purchased from StemExpress...”
Direct StemExpress PBMC citation
Automated generation of immature dendritic cells in a single use system
Journal of Immunological Methods · 2018
Whole blood purchased from StemExpress was processed to isolate PBMCs for dendritic cell generation experiments.
“A unit of whole blood ... was purchased from StemExpress ... The blood was then immediately separated using Ficoll density gradient medium to extract the PBMCs.”
PBMCs isolated from StemExpress whole blood
Dendritic cell mimicking scaffolds for ex vivo T cell expansion
Materials Today Bio · 2022
Fresh human leukopak purchased from StemExpress was used as the starting material and PBMCs were enriched from it for T cell expansion studies.
“Fresh human peripheral blood Leukopak ... was purchased from StemExpress ... PBMCs were enriched from Leukopak in a Ficoll gradient.”
PBMCs derived from StemExpress leukopak
PBMC based immune response modulation in cancer research
Cancer Biology & Therapy · 2025
PBMCs were used to evaluate immune response modulation and therapeutic targeting strategies in cancer models.
PBMC · Immunotherapy
PBMC driven immune signaling and functional analysis
Research PDF
PBMCs were used to analyze immune signaling pathways and cellular response mechanisms.
PBMC · Immune Signaling
Leukopaks
Selected publications demonstrating the use of human leukopak sourced material in immunology, cell therapy, and translational research workflows, including studies using StemExpress-supplied leukopaks.
Bacterial pathogen-associated molecular patterns upregulate glucocorticoid receptor alpha in human leukopak PBMCs
Shock · 2022
Leukopak-derived PBMCs were used to study inflammatory cytokine responses following stimulation with bacterial pathogen-associated molecular patterns.
Leukopak PBMCs · Innate Immunology
TSCM-predominant allogeneic anti-BCMA CAR-T therapy for relapsed/refractory multiple myeloma
Nature Communications · 2025
Fresh leukopaks from healthy donors were used as starting material for T cell isolation and CAR-T manufacturing workflows.
“Fresh leukopaks from HDs were sourced from various providers ... StemExpress...”
Leukopak · T Cells · CAR-T
Differential regulation of Treg stability by TGFβ signaling
Frontiers in Immunology · 2025
Leukopaks were used to isolate PBMCs and sort human regulatory T cell subsets for functional analysis.
“Leukopaks from healthy donors were obtained from StemExpress...”
Leukopak · PBMC Isolation · Treg
Mobilized Peripheral Blood
Selected publications demonstrating the use of mobilized peripheral blood and mobilized leukopak-derived CD34+ hematopoietic stem and progenitor cells in gene therapy, cell therapy, and transplantation workflows.
Hematopoietic reconstitution dynamics of mobilized peripheral blood-derived stem cells after gene therapy
Nature Communications · 2023
Mobilized peripheral blood-derived hematopoietic stem and progenitor cells were used for gene therapy, demonstrating improved engraftment and recovery.
Mobilized Blood · HSPC · Gene Therapy
In vivo CRISPR gene editing in hematopoietic stem cells
Nature Biotechnology · 2022
Mobilized CD34+ hematopoietic stem cells were used in CRISPR-based gene editing workflows for therapeutic applications.
CD34+ Cells · CRISPR · Gene Editing
Ex vivo expansion and functional characterization of hematopoietic stem cells
Stem Cell Research · 2023
Mobilized peripheral blood-derived hematopoietic stem cells were expanded ex vivo and evaluated for functional and therapeutic potential.
HSPC · Expansion · Stem Cell Biology
Optimized lentiviral production and transduction of primary human cells
Molecular Therapy Methods & Clinical Development · 2024
Mobilized CD34+ cells were transduced using optimized viral production systems for gene and cell therapy workflows.
CD34+ Cells · Viral Transduction
Improved workflows for gene modification in hematopoietic stem cells
Molecular Therapy Methods & Clinical Development · 2024
Mobilized hematopoietic stem cells were used to evaluate improved gene modification and cell engineering workflows.
Gene Editing · HSPC
Mobilized peripheral blood stem cells in transplantation and hematologic recovery
Blood · 2023
Mobilized peripheral blood stem cells were used in transplantation workflows to evaluate hematologic recovery and clinical outcomes.
Transplantation · Mobilized Blood
Bone Marrow
Selected publications demonstrating the use of human bone marrow and bone marrow derived cells sourced from StemExpress in stem cell, immunology, and regenerative medicine research.
Identification of osteogenic progenitor cell-targeted peptides that augment bone formation
Nature Communications · 2020
Bone marrow aspirates were used to study osteogenic progenitor targeting and bone formation mechanisms.
“Bone marrow aspirates were obtained from healthy human donors (StemExpress...)”
Bone Marrow · Regenerative Medicine
Subretinal versus intravitreal administration of human CD34+ bone marrow-derived stem cells
Annals of Translational Medicine · 2021
Bone marrow derived CD34+ stem cells were used to evaluate regenerative therapies in retinal degeneration models.
“Fresh bone marrow from a healthy human donor was obtained from StemExpress...”
CD34+ Cells · Stem Cell Therapy
Optimizing ex vivo expansion of human hematopoietic stem cells
bioRxiv · 2024
Human hematopoietic stem and progenitor cells were expanded under optimized culture conditions to improve growth and gene editing efficiency.
HSC · Gene Editing
Stem cell based approaches in regenerative medicine
Stem Cell Research & Therapy · 2024
Bone marrow derived stem cells were used to study regenerative mechanisms and therapeutic applications.
Stem Cells · Regenerative Medicine
Bone marrow microenvironment and immune regulation
Cell Reports · 2022
Bone marrow derived cells were used to study immune signaling and hematopoietic regulation.
Hematopoiesis · Immunology
Cord Blood / Umbilical Cord
Selected publications demonstrating the use of human cord blood and umbilical cord derived cells sourced from StemExpress in immunology, gene editing, and regenerative medicine research.
Optimizing ex vivo expansion of human hematopoietic stem cells
bioRxiv · 2024
Cord blood derived hematopoietic stem and progenitor cells were expanded under optimized conditions to improve proliferation and gene editing efficiency.
Cord Blood · HSPC · Gene Editing
Stem cell based approaches in regenerative medicine
Stem Cell Research & Therapy · 2024
Cord blood derived stem cells were used to investigate regenerative mechanisms and therapeutic applications.
Cord Blood · Regenerative Medicine
Regulation of hematopoietic stem cells within the immune microenvironment
Cell Reports · 2022
Cord blood derived hematopoietic stem cells were used to study immune signaling and stem cell regulation.
Cord Blood · Hematopoiesis · Immunology
Umbilical cord-derived mesenchymal stem cells reversed the suppressive deficiency of T regulatory cells
Oncotarget · 2016
Umbilical cord derived mesenchymal stem cells were used in co culture with PBMCs to evaluate immune regulatory effects.
Umbilical Cord MSCs · Immunology
Human umbilical cord-derived mesenchymal stem cells suppress proliferation of activated lymphocytes
Cellular Immunology · 2016
Umbilical cord derived mesenchymal stem cells were used to suppress activated PBMC proliferation and modulate cytokine secretion.
“Human umbilical cords (n = 3) were purchased from StemExpress (Placerville, CA).”
Cord Tissue · MSC · Immunology