Potential of CRISPR-Cas9-based Technology to Treat Congenital Amegakaryocytic Thrombocytopenia (CAMT)
A single mutation in a gene can lead to rare inherited diseases, such as cystic fibrosis, Tay-Sachs, and sickle-cell anemia, and are often difficult to treat and, for most, have no cure. However, with the current advances in CRISPR-Cas9 genome engineering technology, it may be possible to introduce new immunotherapies to treat these and other…
For More InformationCGT Global Folsom Celebrates One Year Anniversary
It’s been one year since StemExpress moved our laboratory headquarters from Placerville to Folsom, CA. Our new state-of-the-art facility has enabled us to increase production and meet the growing needs of our clients. We thank our dedicated staff, the community of Folsom, and our clients for making the past year a successful one.
For More InformationDirected differentiation of human bone marrow MSCs to functional Schwann cells
The peripheral nervous system (PNS) comprises many complex cell types that work together to transmit electrical signals from the body’s sensory receptors to the central nervous system (CNS) and vice versa. Peripheral nerve cells relay the electrical signals through the long, thin part of the cell called an axon. Schwann cells create nodes of myelin…
For More InformationTreating the side effects of chemotherapy
The human body has many lines of defense against infection, keeping us healthy and free of disease. One immediate line of defense is the innate immune system, which is comprised of white blood cells that are ready to fight against bacterial or fungal infection at birth. One of the most numerous and important cells of…
For More InformationHow CAR-T cell therapy works
On August 30, 2017, the FDA approved the first US CAR-T cell therapy for the treatment of ALL patients. According to FDA Commissioner Dr. Scott Gottlieb, “We’re entering a new frontier in medical innovation with the ability to reprogram a patient’s own cells to attack a deadly cancer.” Check out this brief video about how…
For More InformationMake finding the right human biospecimen easy!
Remove the waiting and the endless paperwork that comes with collecting human biospecimens. With StemExpress’ robust donor pool, we make finding the right donor for your research a simple and straightforward process. StemExpress has partnered with iSpecimen Marketplace to enhance that connection via a straightforward online resource. Through this partnership, StemExpress enhances its capabilities to…
For More InformationCGT Global in The Sacramento Bee!
How can a single donation of blood for research impact the research community? With the partnership between StemExpress and researchers around the world, one sample can do a lot! “One patient could help a disease study in multiple places versus just being limited to one researcher at one university,” according to Dr. Michael Chez, a…
For More InformationCGT Global in the Sacramento Bee!
[vc_row][vc_column][vc_column_text] How can a single donation of blood impact the research community?With the partnership between StemExpress and researchers around the world, one sample can do a lot! “One patient could help a disease study in multiple places versus just being limited to one researcher at one university,” according to Dr. Michael Chez, a pediatric neurologist…
For More InformationA New Approach to Treating Myelodysplastic Syndrome
Myelodysplastic syndrome (MDS) is a group of bone marrow disorders where the bone marrow is incapable of producing healthy mature blood cells. Through a process called hematopoiesis, blood stem cells or hematopoietic stem and progenitor cells (HSPC) within the bone marrow give rise to blood cells, such as white blood cells, platelets, and red blood…
For More InformationIntegration of Large Transgenes into the Genome of Hematopoietic Primary Cells
RNA-guided CRISPR-Cas9 nuclease is a genome-editing tool that allows researchers to edit parts of the genome by removing, adding, or altering sections of the DNA sequence. CRISPR-Cas9 targets double-stranded DNA using single guided RNA (sgRNA) that shepherds the nuclease to the target DNA sequence. Once at the target, CRISPR-Cas9 creates a double-stranded DNA break. Consequently,…
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