Macrophages

Macrophages are large phagocytic cells that play a crucial role in the innate immune system.  Derived from monocytes, they are found in nearly all tissues:

• Engulf and digest pathogens (like bacteria, viruses, and fungi), dead cells, and cellular debris through phagocytosis.
• Activate immune responses by secreting signaling molecules (cytokines) that attract other immune cells to sites of infection or injury.
• Present antigens to T cells, functioning as antigen-presenting cells (APCs) that help coordinate adaptive immune responses.

Macrophages are essential for clearing infections, wound healing, and maintaining tissue health by removing dead or damaged cells.