Peripheral Blood CD8+CD45RA+ Naïve Cytotoxic T Cells, Frozen

Human peripheral blood CD8+CD45RA+ naïve cytotoxic T cells are enriched in a multi-step process by means of negative and positive selection. Isolated cells are characterized by flow cytometry to ensure a highly pure and viable cell population.

Cells were obtained using Institutional Review Board (IRB) approved consent forms and protocols.

Since our founding in 2010, CGT Global has pursued our mission to transform healthcare as we accelerate cell and gene therapy research and clinical trials, streamline the commercialization of new treatments, and map the last mile to patient access to these life-changing remedies.  By innovating each stage in the cycle; development, commercialization, and delivery, we reduce the overall cost of the care and multiply access points so that millions can receive cutting edge, life-saving gene and cell therapies.

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Description

Human CD8+CD45RA+ naïve cytotoxic T cells are mature T cells that have yet to be exposed to an antigen presented on the MHC class I molecule of an antigen-presenting cell (APC). Once activated, CD8+ cytotoxic T cells defend the body against intracellular pathogens, such as viruses and bacteria, as well as cancerous cells by releasing cytotoxins that result in apoptosis of the infected or diseased cell.

 

Additional information

Anticoagulant

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Donor Attributes

Product Information Sheet

 

Figure 1. Representative flow data of enriched CD8+CD45RA+ naive cytotoxic T cells from peripheral blood prior to cryopreservation.