Innovation & Emerging Technologies
All About B Cells: Antibodies and Beyond
Written by Joanna Wirkus, PhD Introduction B cell basics B cell differentiation Antibodies Monoclonal antibodies in medicine Cytokine production Antigen presentation B cells and gene therapy: animal and human research B lymphocytes were first described in the 1960s by scientists Cooper and Good, who discovered the site of B cell maturation in birds by halting…
For More InformationHow to Improve Humanized Mouse Engraftment: CD34+ Cell Sourcing & Viability Tips
By: Joanna Wirkus Simple Steps to Significantly Improve Humanized Mice Engraftment Success Previously in “Overcoming Challenges with Animal Models in Research”, we covered why animal models with human immune systems have significantly improved the translation of preclinical findings into life-saving treatments. Successfully creating these advanced models for testing new therapies relies on high hematopoietic stem…
For More InformationCryopreservation in Cell and Gene Therapy: Ensuring High-Viability Cells for Research & Manufacturing
By Joanna Wirkus The Role of Cryopreservation in Cell and Gene Therapy Cryopreservation is a cornerstone of cell and gene therapy, enabling the long-term storage and viability of vital cell types such as CD34+ hematopoietic stem cells, mesenchymal stem cells (MSCs), natural killer (NK) cells, and T cells used in CAR-T therapies. Interestingly, nature has…
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