CGT Global Blog
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Stay ahead in the dynamic world of Accelerating Cell and Gene Therapy with the CGT Global blog and news page. Explore insightful articles, industry updates, product updates, and expert analysis on all things CGT Global. Stay informed, inspired, and connected with CGT Global – your go-to source for cutting-edge insights in the ever-evolving realm of research, clinical projects and healthcare.
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What do you wish people knew about your condition? Illness and disease affect our lives in so many different ways, and no two experiences are the same. You could write about how you or a loved one has been affected by disease, why you chose to participate in medical research, or what you hope will be cured in the future. If you want to share your story with us, but do not want it published on the StemExpress Foundation Blog, just let…
Read MoreLUNG CANCER PROJECT
The ever-present goal of the StemExpress Foundation is to improve the lives and outcomes of patients with all kinds of diseases. To that end, we are excited to be participating in a new lung cancer project! Researchers have created a new diagnostic tool to detect lung cancer earlier and in a less invasive way than traditional biopsies. In order to make this new screening available to the public, these scientists need small samples of blood from people with lung cancer so that…
Read MoreCGT Global Folsom Celebrates One Year Anniversary
It’s been one year since StemExpress moved our laboratory headquarters from Placerville to Folsom, CA. Our new state-of-the-art facility has enabled us to increase production and meet the growing needs of our clients. We thank our dedicated staff, the community of Folsom, and our clients for making the past year a successful one.
Read MoreDirected differentiation of human bone marrow MSCs to functional Schwann cells
The peripheral nervous system (PNS) comprises many complex cell types that work together to transmit electrical signals from the body’s sensory receptors to the central nervous system (CNS) and vice versa. Peripheral nerve cells relay the electrical signals through the long, thin part of the cell called an axon. Schwann cells create nodes of myelin sheath around the axon called nodes of Ranvier. Between each node is a break essential for increasing the speed of which the electrical signal travels between distant…
Read MoreTreating the side effects of chemotherapy
The human body has many lines of defense against infection, keeping us healthy and free of disease. One immediate line of defense is the innate immune system, which is comprised of white blood cells that are ready to fight against bacterial or fungal infection at birth. One of the most numerous and important cells of the innate immune system is phagocytic granulocytes or neutrophils. These cells spend most of their lives circulating in the peripheral blood, but once stimulated by a sequence…
Read MoreHow CAR-T cell therapy works
On August 30, 2017, the FDA approved the first US CAR-T cell therapy for the treatment of ALL patients. According to FDA Commissioner Dr. Scott Gottlieb, “We’re entering a new frontier in medical innovation with the ability to reprogram a patient’s own cells to attack a deadly cancer.” Check out this brief video about how CAR-T cell therapy works. At StemExpress we offer human blood products such as whole blood and Leukopaks as well as peripheral blood CD3+, CD4+, and CD8+ T cells. Purified primary CD3+, CD4+, and…
Read MoreMake finding the right human biospecimen easy!
Remove the waiting and the endless paperwork that comes with collecting human biospecimens. With StemExpress’ robust donor pool, we make finding the right donor for your research a simple and straightforward process. StemExpress has partnered with iSpecimen Marketplace to enhance that connection via a straightforward online resource. Through this partnership, StemExpress enhances its capabilities to reach scientists that require a diverse selection of human samples ranging from frozen tumors to blood samples. StemExpress and iSpecimen Marketplace are working together to bring you…
Read MoreA New Approach to Treating Myelodysplastic Syndrome
Myelodysplastic syndrome (MDS) is a group of bone marrow disorders where the bone marrow is incapable of producing healthy mature blood cells. Through a process called hematopoiesis, blood stem cells or hematopoietic stem and progenitor cells (HSPC) within the bone marrow give rise to blood cells, such as white blood cells, platelets, and red blood cells. In an individual with MDS the HSPCs fail to mature and either die in the bone marrow or soon after they enter the bloodstream. The lack…
Read MoreIntegration of Large Transgenes into the Genome of Hematopoietic Primary Cells
RNA-guided CRISPR-Cas9 nuclease is a genome-editing tool that allows researchers to edit parts of the genome by removing, adding, or altering sections of the DNA sequence. CRISPR-Cas9 targets double-stranded DNA using single guided RNA (sgRNA) that shepherds the nuclease to the target DNA sequence. Once at the target, CRISPR-Cas9 creates a double-stranded DNA break. Consequently, the hosts own DNA repair mechanisms, such as non-homologous end-joining (NHEJ) or homology-directed repair (HDR), repairs the break. To alter or correct a dysfunctional gene CRISPR-Cas9 nuclease…
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