CGT Global Blog

CGT Global News

Stay ahead in the dynamic world of Accelerating Cell and Gene Therapy with the CGT Global blog and news page. Explore insightful articles, industry updates, product updates, and expert analysis on all things CGT Global. Stay informed, inspired, and connected with CGT Global – your go-to source for cutting-edge insights in the ever-evolving realm of research, clinical projects and healthcare.

Baby KJ Makes Headlines as the First Infant to Receive Personalized CRISPR Gene Editing Therapy

Baby KJ Makes Headlines as the First Infant to Receive Personalized CRISPR Gene Editing Therapy

September 10, 2025

Written by Joanna Wirkus, PhD Today, NPR ’s Science Friday spotlighted Baby KJ, the first infant to receive a personalized CRISPR-based gene editing treatment. The segment explored the groundbreaking therapy, the condition it aims to treat, and the collaborative effort behind this historic milestone. Here’s a summary of the key points from the report: What is Baby KJ’s Illness? What Are the Current Treatment Options? How Long Did FDA Approval Take? What Were Conversations Like With KJ’s Parents? How Was CRISPR Gene…

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Alzheimer’s & Neurodegenerative Disease: A Global Challenge

Alzheimer’s & Neurodegenerative Disease: A Global Challenge

September 10, 2025

Written by CGT Global Cell & Gene Therapy Is Shifting the Paradigm Recent CGT innovations are upending traditional models and opening new paths to treat or even reverse Alzheimer’s progression: 1. AAV-Based Gene Therapy (LX1001) 2. CRISPR-Engineered Microglia 3. Behavior-Reprogramming Gene Therapy (UC San Diego) 4. Stem Cells & MSC Therapies 5. iPSC TriCulture Models for Neuroinflammation 6. Targeting GlialMediated Inflammation Why This Matters for CGT & You The Road Ahead Final Word The convergence of CGT technologies—AAV vectors, CRISPR, iPSC, and…

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Mesenchymal Stem Cell Derived Exosomes: Revolutionizing Future Medical Treatments

Mesenchymal Stem Cell Derived Exosomes: Revolutionizing Future Medical Treatments

September 10, 2025

Why are scientists excited about Mesenchymal Stem Cell Exosomes? Mesenchymal stem cell (MSC) exosomes are on the brink of revolutionizing future treatments for chronic diseases and injuries. These microscopic biological messengers represent a vital mechanism of cellular communication, potentially offering a biomolecular reset for human physiological processes. The Unique Capabilities of Mesenchymal Stem Cells Mesenchymal stem cells possess unique adaptive properties and profound regenerative abilities. They can: Part of MSCs healing properties is their capacity to: Clinical Progress and Regulatory Validation for…

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CGT Global Welcomes Dr. Jerome Ritz to Its Board of Advisors, Enriching Knowledge of Cellular Therapies and Hematology

August 14, 2025

By:CGT GlobalviaBusiness Wire August 14, 2025 at 09:00 AM EDT CGT Global, a biotechnology leader accelerating access to life-changing cell and gene therapies, today announced the appointment of Jerome Ritz, MD, to its Board of Advisors. Dr. Ritz brings a distinguished career in hematology, oncology, cell manufacturing, and the advancement of cell and gene therapies. This press release features multimedia. View the full release https://apnews.com/press-release/business-wire/cgt-global-welcomes-dr-jerome-ritz-to-its-board-of-advisors-enriching-knowledge-of-cellular-therapies-and-hematology-3250b55a87174e3b9376fb1b67567208# CGT Global Welcomes Dr. Jerome Ritz to Its Board of Advisors Dr. Ritz received his MD from…

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CGT Global Appoints Dr. Andrew Branagan to Board of Advisors, Expanding Cell and Gene Therapy Expertise

August 11, 2025

CGT Global, a leading biotechnology company driving the development and delivery of innovative cell and gene therapies, today announced the appointment of Andrew Robert Branagan, MD, PhD, to its Board of Advisors. Dr. Branagan brings extensive expertise in hematologic malignancies, immunology, and the development of novel therapeutic strategies, including cellular therapies. This press release features multimedia. View the full release here: CGT Global Appoints Dr. Andrew Branagan to Board of Advisors, Expanding Cell and Gene Therapy Expertise | Boston Herald – Boston news,…

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Meet CGT Global's Scientific Team: Bryan Pulling – Laboratory Operations Manager Part II

Behind the Scenes at CGT Global’s Laboratory: Life in the Lab with Bryan

July 23, 2025

By Joanna Wirkus, PhD CD34+ Cell Isolation Process Previously in our Meet the Scientific Team blog, we gained insight into the background of CGT Global’s Laboratory Operations Manager in Folsom, California — Bryan — and his inspiration for his work. Today, we go behind the scenes, or behind the bench, to see what a day in the life of a cell biologist really looks like and how CD34+ stem cells are isolated at CGT Global’s laboratories. Bryan Pulling – Laboratory Operations Manager…

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Meet CGT Global's Scientific Team: Bryan Pulling – Laboratory Operations Manager

Meet CGT Global’s Scientific Team: Bryan Pulling – Laboratory Operations Manager

July 15, 2025

Written by Joanna Wirkus, PhD Every day at CGT Global, our experienced team collaborates to deliver high quality cells to scientists around the world. Success starts with the strength of our team and the dedication of the people who power it. In this edition of Meet the Scientific Team, we’re proud to spotlight Bryan Pulling — the brains behind the bench. Today, Bryan — CGT Global’s Laboratory Operations Manager in Folsom, California — shares his background and his inspiration for his work.…

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Fast-Track Your Therapy Pipeline with CGT Global’s Clinical Capabilitie

Fast-Track Your Therapy Pipeline with CGT Global’s Clinical Capabilities

July 11, 2025

By: Joanna Wirkus  Despite exponential progress in the field of biology, inherited and preventable diseases continue to burden billions of people worldwide. Bridging the gap between laboratory discoveries and transformative clinical therapies remains a significant challenge, , and an urgent opportunity. High-quality biospecimens are foundational to this effort, enabling the advancement of cell and gene therapy research and powering the development of next-generation treatments like CAR-T cell therapy for life-threatening conditions like hematopoietic malignancies.  For over 15 years, scientific innovators across the…

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All About B Cells: Antibodies and Beyond

All About B Cells: Antibodies and Beyond

July 11, 2025

Written by Joanna Wirkus, PhD Introduction  B cell basics  B cell differentiation  Antibodies  Monoclonal antibodies in medicine Cytokine production Antigen presentation  B cells and gene therapy: animal and human research  B lymphocytes were first described in the 1960s by scientists Cooper and Good, who discovered the site of B cell maturation in birds by halting antibody production after irradiating the Bursa of Fabricius in chicks. Much has been discovered about B cells in the past 60 years, but they remain incompletely understood…

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When Politics Blocks Progress: Funding Health Discoveries in Peril

When Politics Blocks Progress: Funding Health Discoveries in Peril 

July 10, 2025

Shifting Political Priorities Threaten the Bedrock of Health Science Investment  By: Joanna Wirkus PhD  July 2025  ** For scientists under pressure from shifting funding priorities, CGT Global has curated a FREE downloadable funding toolkit with resources to support your long-term funding acquisition strategy. Complete with a grant planning checklist, a curated list of 35+ funding opportunities, and a funding tracking spreadsheet – for preclinical to clinical researchers, visa holders, and graduate student through distinguished professors.  =======================================================================  ~50% of global biomedical research is…

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CGT Sourcing Guide 2025: How to Build a Resilient Supply Chain Amid Tariff Pressures By CGT Global

CGT Sourcing Guide 2025: How to Build a Resilient Supply Chain Amid Tariff Pressures

June 4, 2025

By CGT Global The latest round of U.S. tariffs didn’t just shake up the headlines—it shook the very foundations of global pharma supply chains. And while most of the buzz has focused on traditional drugmakers, let’s be clear: cell and gene therapy manufacturers aren’t sitting this one out. For companies working with high-value, time-sensitive materials like Leukopaks, PBMCs, CD34+ cells, and viral vectors, even subtle disruptions can have massive downstream consequences. Now, with added costs, uncertain delivery timelines, and sourcing challenges entering…

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blog picture for nk cancer cells

How Natural Killer Cells are Revolutionizing Cancer Treatment

May 23, 2025

By Joanna Wirkus What makes Natural Killer (NK) Cells the Perfect Weapon Against Cancer? Unlike the T cells of the adaptive immune system, innate natural killer (NK) cells protect the body against tumors without prior programming. They recognize and become activated by abnormal cells that lack or express key outer membrane markers characteristic of cancer. One way NK cells initiate malignant cell death is by unleashing granules of membrane penetrating perforins and caspase-activating, apoptosis-initiating granzymes. Their inherent anti-cancer abilities make NK cells…

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