Bone Marrow CD133+ Stem/Progenitor Cells, Frozen
Bone Marrow CD133+ Stem/Progenitor Cells, Frozen
The CGT Global Difference
CGT Global is a Biospecimen Provider for a wide range of clinical and preclinical research projects. Our state-of-the-art laboratories and collection centers are located nationwide and provide end-to-end services: These services include:
- Process, isolate, and cryopreserve cells immediately after donor collection
- Amazing customer service and fast shipping
- Customize products to distinct study specifications
- Retain specific donor demographics and a safe, highly recallable donor pool
- HLA Typed Primary Cells
- Biobanked cells
Description
Human CD133 is a transmembrane glycoprotein that is expressed on CD34+ and CD34- multipotent stem and progenitor cells that are involved in hematopoiesis. Unlike CD34+ cells, bone marrow CD133+ cells are involved in vasculogenesis giving rise to endothelial cell precursors. Additionally, bone marrow CD133+ hematopoietic cells have been found to differentiate in vitro to cells of the ectodermal and mesodermal lineages implying that these cells have the ability to give rise to cells of non-hematopoietic lineages.
Bone marrow mononuclear cells (MNCs) are separated from whole bone marrow by a density gradient centrifugation protocol. CD133+ stem and progenitor cells are positively selected using immunomagnetic anti-CD133 (clone AC133) microbeads from the MNC population. CD133+ cells characterized by flow cytometry before cryopreservation to ensure a highly pure and viable cell population.
Cells were obtained using Institutional Review Board (IRB) approved consent forms and protocols.
Additional information
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