Posts by drivendigital
CGT Global in the Sacramento Bee!
[vc_row][vc_column][vc_column_text] How can a single donation of blood impact the research community?With the partnership between StemExpress and researchers around the world, one sample can do a lot! “One patient could help a disease study in multiple places versus just being limited to one researcher at one university,” according to Dr. Michael Chez, a pediatric neurologist…
For More InformationA New Approach to Treating Myelodysplastic Syndrome
Myelodysplastic syndrome (MDS) is a group of bone marrow disorders where the bone marrow is incapable of producing healthy mature blood cells. Through a process called hematopoiesis, blood stem cells or hematopoietic stem and progenitor cells (HSPC) within the bone marrow give rise to blood cells, such as white blood cells, platelets, and red blood…
For More InformationIntegration of Large Transgenes into the Genome of Hematopoietic Primary Cells
RNA-guided CRISPR-Cas9 nuclease is a genome-editing tool that allows researchers to edit parts of the genome by removing, adding, or altering sections of the DNA sequence. CRISPR-Cas9 targets double-stranded DNA using single guided RNA (sgRNA) that shepherds the nuclease to the target DNA sequence. Once at the target, CRISPR-Cas9 creates a double-stranded DNA break. Consequently,…
For More InformationImportant Oversight on Human Germline Genome Editing
In light of the recent article published in Nature, human germline genome editing in the US has taken a front and center stage in the ethical principles and scientific boundaries of modern science. Researchers at the Oregon Health and Science University (OHSU) in Portland, led by reproductive biologist Shoukhrat Mitalipov, corrected a gene mutation responsible…
For More InformationCGT Global Signs Distribution Agreement with CliniSciences
StemExpress is a premier provider of human blood-derived cell products, including bone marrow, cord blood, peripheral blood, Leukopaks and Mobilized Leukopaks. To continue meeting the needs of clients abroad, StemExpress has expanded its global capabilities to Europe through a distribution agreement with CliniSciences, a supplier of research and in-vitro diagnostic products, that pride themselves in…
For More InformationHumanized Mice for HIV Research
According to the World Health Organization (WHO), approximately 36.7 million people are living with HIV and one million have died due to a failing immune system in 20161. Currently, antiretroviral treatment therapy is used to prevent disease progression, but a cure has perplexed scientist for over 40 years. To find a cure, improvements in the…
For More InformationFinding a Target in Pancreatic Cancer
Pancreatic ductal adenocarcinoma (PDA) is an aggressive and difficult malignancy to treat and accounts for one of the highest cancer death rates in the US. PDA encompasses 85% of all pancreatic cancers and has a 5% survival rate five years after diagnosis. Given the severity of the disease, it is imperative to find a cure…
For More InformationGeneration of Large Intestinal Organoid
The workings of the human body have long been studied, ranging from the development of an organism to the diseases that inevitably bring about their demise. Much of the research into the mechanisms of development and disease utilizes cell lines or animals such as mice. Although scientific advances have been made using these model systems,…
For More InformationImprovements in NIPS Results from Maternal Blood
Chromosome aneuploidies are common genetic defects that can lead to diseases such as Down syndrome. Current methods of aneuploidy testing exist, primarily in the form of chorionic villus sampling or amniocentesis. Although precise, these tests are invasive and may result in intrauterine infection and miscarriage. Recently, fetal genetic material (found in maternal blood) has been…
For More InformationSynthetic Stem Cells Mend Damaged Heart Tissue
Adult stem cells have the ability of self-regeneration and differential plasticity, which allows them to play a key role in cell-mediated cardiovascular regenerative therapies. One such adult stem cell, mesenchymal stem cell (MSC), is widely used in preclinical and clinical studies on the regeneration of cardiac function and structure after acute myocardial infarction. A primary…
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