Peripheral Blood CD19+ B Cells, Frozen
Peripheral Blood CD19+ B Cells, Frozen
The CGT Global Difference
CGT Global is a Biospecimen Provider for a wide range of clinical and preclinical research projects. Our state-of-the-art laboratories and collection centers are located nationwide and provide end-to-end services: These services include:
- Process, isolate, and cryopreserve cells immediately after donor collection
- Amazing customer service and fast shipping
- Customize products to distinct study specifications
- Retain specific donor demographics and a safe, highly recallable donor pool
- HLA Typed Primary Cells
- Biobanked cells
Description
Human B cells are lymphocytes that are characterized by the expression of CD19 on the cell surface. These cells are one of the main cell types involved in the humoral immune response. Upon activation, due to an encounter with an antigen, B cells will act as antigen-presenting cells (APCs), make antibodies against foreign antigens, and develop into memory B cells or plasma cells.
Human peripheral blood CD19+ B cells are isolated from the mononuclear cell fraction by means of negative selection. Cells expressing CD2, CD14, CD16, CD36, CD43, and CD235a are depleted from the mononuclear cell population using immunomagnetic particles leaving purified, untouched CD19+ B cells. Isolated cells are characterized by flow cytometry before cryopreservation to ensure a highly pure and viable cell population.
*Our CD19+ B Cells are isolated by means of negative selection. However, we do offer the isolation of CD19+ B cells by positive selection as a custom order. Please inquire to obtain pricing for the positive selection of CD19+ B cells.
Cells were obtained using Institutional Review Board (IRB) approved consent forms and protocols.
Learn more about bulk ordering through CGT Global HERE
Additional information
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Product Information Sheet
Certificate of Analysis
Material Safety Data Sheet
Protocols
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Figure 1. Representative histogram of enriched CD19+ B cells from peripheral blood prior to cryopreservation.
