Peripheral Blood CD4+CD25+ Regulatory T Cells, Frozen
Peripheral Blood CD4+CD25+ Regulatory T Cells, Frozen
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CGT Global is a Biospecimen Provider for a wide range of clinical and preclinical research projects. Our state-of-the-art laboratories and collection centers are located nationwide and provide end-to-end services: These services include:
- Process, isolate, and cryopreserve cells immediately after donor collection
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- Customize products to distinct study specifications
- Retain specific donor demographics and a safe, highly recallable donor pool
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Description
Peripheral blood regulatory T cells (T-regs) are a subpopulation of T cells that play an important role in maintaining self-tolerance in the adaptive immune system by suppressing potentially deleterious activities of CD4+ helper T cells, which, if not regulated, can cause a variety of autoimmune disorders.
Human Peripheral Blood CD4+CD25+ Tregs are enriched in a multi-step process by means of both positive and negative selection. Isolated cells are characterized by flow cytometry before cryopreservation to ensure a highly pure and viable cell population.
Cells were obtained using Institutional Review Board (IRB) approved consent forms and protocols.
Additional information
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Figure 1. Representative flow data of peripheral blood enriched CD4+CD25+ Tregs prior to cryopreservation.
Schillebeeckx et al. (2020) Analytical Performance of an Immunoprofiling Assay Based on RNA Models. J Mol Diagn. doi.org/10.1016/j.jmoldx.2020.01.009.
